Alice the Great is Little Bill's great grandmother. She is Brenda and Deborah's grandmother. Alice the Great has an older brother and older sister, and a cousin who lives in Cincinnati. Usually she teaches Little Bill lessons and tells stories to him. Alice has a friend named Emmaline, Monty's grandmother. She is voiced by the late Ruby Dee.
Alice the Great is most likely in her seventies, but she's still spry, sharp, and energetic. She worked for years as a home attendant nurse and although she's now an old woman, Alice has no intention of slowing down.